those on aspartame support groups
who have had questions about the liver problems
and why some physicians question hepatitis in aspartame
James Bowen, M.D. June 4, 2001
Hepatitis, characterized by an accumulation of fat
in the hepatocyte (liver cell) resulting from ingestion
of aspartame is focused in the mitochondria. Mitochondria
are the energy furnaces of the cell and aspartame
(APM) metabolism into more toxic derivatives, formaldehyde
and formic acid take place in the mitochondria. As
in all NutraSweet poisoning the formaldehyde and formic
acid immediately attack the tissues they are generated
in so we see a new co-existent plague of "anti-mitrochondrial
antibody hepatitis" generated right along with the
steato hepatitis because the immune system reacts
to the degenerated tissues.
The breakdown of fats into energy producing chemicals
has obligatory metabolism via mitochondrial mechanisms.
When mitochondria are rendered defective by aspartame
poisoning fat cannot be processed to be used for energy.
The formation of fat from dietary calories proceeds
because fat is built up directly in the cytosol of
cells and accumulation is not dependent on mitochondrial
function. So liver cells and fat cells and after fats
cells (lipocytes) store fat and cannot get rid of
it no matter how badly it is needed to supply energy
to the body.
to NutraSweet these victims literally cannot starve
the fat off of their bodies or out of their livers
because of their compromised mitochondrial functional
capacity. To make matters worse the mitochondrial
DNA is severely damaged.
poisoning occurring as the direct result of the obligatory
metabolism of methyl radicals is the most common form
of genetic damage, caused by formaldehyde cross linkage
of DNA strains. The mitochondrial DNA is thousands
of times more vulnerable to this than nuclear DNA,
and lack the excellent repair mechanisms that protects
the integrity of nuclear DNA. The presently understood
mitochondria DNA repair mechanisms are merely excisional,
that is the DNA rendered abnormal by the aspartame/methanol
poisoning is merely excised leaving the mitochondrial
function at best insufficient, defective and incomplete.
Which in addition to producing inadequate and incomplete
energy metabolism spins off highly damaging free radicals.
Methanol/formaldehyde poisoning is noted for this.
This vicious circle amounts to tremendous degenerative
process in the human organism and the unfortunate
results too numerous to be repeated here but are well
detailed on dorway.com
and other excellent sites such as holisticmed.com,
as well as Dr. Hyman Roberts text on the subject.
(Aspartame Disease: The Ignored Epidemic - 1 800 814
- 9800 or www.sunsentpress.com
amounts to virtual "genocide", and is further emphasized
by the fact this mitochondrial DNA damage is directly
transmitted by female NutraSweet users to her children
and grandchildren, and to subsequent generations via
her female descendents.