fat accumulation in the liver. The liver removes fatty acids from
the diet or from accumulated fat deposits by degrading and oxidizing
them when the body must call on fat as a major energy source. Lipotropic
factors must be active to prevent abnormal accumulation of fats
in the liver. By a process called transmethylation, these lipotropic
agents promote the production of lipoproteins, which transfer the
fatty acids out of the liver. (62)
fat is 5-15%, whereas, a diabetic's liver consists of 25-35% fat.
The percentage of liver fat may also be increased by:
Excessive alcohol consumption
Birth control pills
High vitamin B-1 and B12 intake
that can result from liver dysfunction include:
Blood sugar metabolic imbalance
also occurs in the liver. By keeping the liver healthy, Lipotrope
aids in this reaction. Estrogen can be carcinogenic if it is not
conjugated. Calcium, protein, mineral, and fat metabolism are all
regulated by components of conjugated estrogen. An unhealthy, fatty
or cirrhotic liver cannot perform these functions efficiently.
to the protective and regenerative milk thistle herb, Lipotrope
includes specific vitamins, minerals, amino acids and herbs, each
of which is targeted to lipid metabolism and healthy liver function.
These nutrients aid the liver and gallbladder in metabolism of lipids
and conjugation of hormones such as estradiol:
is considered one of the B vitamins. It functions with inositol
as a basic constituent of lecithin. It appears to be associated
primarily with utilization of fats and cholesterol in the body.
It prevents fats from accumulating in the liver and facilitates
the movement of fats into the cells. Choline combines with fatty
acids and phosphoric acid within the liver to form lecithin. It
improves liver and gallbladder function and helps prevent gallstones.
like choline, is a constituent of lecithin, which is needed to move
fats from the liver to the cells. High intake of caffeine may create
an inositol shortage in the body. (63)
is involved in the metabolism of fats and fatty acids, especially
the essential unsaturated fatty acids. Birth control pills increase
the risk of gallstones, which can be caused by oxalic acid toxicity.
Vitamin B-6 detoxifies oxalic acid. (67)
and Folic Acid are used in the synthesis of methionine and choline.
The coenzyme of vitamin B-12 is a carrier of methyl groups and hydrogen
and is necessary for carbohydrate, protein, and fat metabolism.
Because of its methyl transfer role, vitamin B-12 is active in the
synthesis of the amino acid methionine from its precursor, homocysteine.
The coenzyme transfers methyl groups from methyl folate, a derivative
of folic acid, to homocysteine and methionine is formed. Because
methionine is needed in choline synthesis, B-12 plays a secondary
role in the lipid pathway. A choline deficiency that causes fatty
liver can be prevented by vitamin B-12 and the other methyl donors:
betaine, methionine, and folic acid. (63)
(para-aminobenzoic acid) stimulates the bacteria in the intestines,
enabling them to produce folic acid, which in turn aids in the production
of pantothenic acid. (63)
Acid has clinical application in lipogenesis formation of cholesterol,
formation of steroid hormones and detoxification of drugs. (62)
is necessary for coenzyme A reaction. This mineral has been shown
to enhance enzymatic activity in the liver. (64) Vitamin and trace
mineral deficiencies lower coenzyme activity. (61). In case studies,
magnesium has been credited with dissolving gallstones. (67) Alcohol
consumption increases the dietary need for magnesium threefold.
is primarily used as a liver-detoxifying herb for the treatment
of hepatitis, jaundice, cancer, psoriasis, eczema, and skin problems.
is a mild stimulant for the bowels and a tonic that strengthens
or invigorates organs or the entire organism. This herb has a beneficial
effect on the kidneys and liver, including acute and chronic liver
inflammation and cirrhosis of the liver. (66) It has been used successfully
in treating menstrual disorders, hepatic derangements, jaundice,
enlarged spleen and jaundice with arrest of menses. (65)
appears to help speed up the flow of bile and has a detoxifying
effect on the liver and spleen. (67)
have been found to increase bile flow as well as aid in carbohydrate
and fat metabolism. (67)
is a source of methyl groups. It is used in the liver for the detoxification
of free radicals and other active by-products. (67)
acts as a methyl donor and antioxidant in liver tissues and aids
healing and detoxification of these tissues. (67) Its primary lipotropic
function is to prevent excess fat accumulations in the liver by
increasing lecithin production. (68)
claim is made for this nutritional preparation. Any recommendations
for its use are based solely upon the discretion of the doctor or
other qualified medical health care practitioner. This information
in this chapter is based upon authoritative and reliable sources.
Lipotrope Formula (per capsule)
treatment I took:
One to two lipotrope capsules three times per day.