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Message - Important notice to Ribavirin users

This information comes from the National Institute of Allergy and Infectious Disease
Ribavirin use poses two significant safty issues:

  1. In animal species ribavirin is significantly teratogenic and /or embrocidal, i.e., an agent that can cause birth defects or kill embryos. Hence, males as well as females who take this drug combination must practice effective contraception both during treatment and for 6 months afterwards. Females should have a negative pregnancy test before beginning therapy.
  2. Ribavirin is associated with a dose-dependent, reversible hemolytic anemia that in the combination study required dose reduction in 7%-10% of patients. Multiple laboratory and clinical evaluations are needed over the coarse of treatment.

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