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The First Naturopathic-Quality Milk Thistle
The Phytosome Process: Phytosomes
™ are advanced forms of herbal products that are better
absorbed and utilized. As a result they are more efficient
and effective than conventional herbal extracts. Phytosomes
™ are produced through a patented process whereby the
individual components of an herbal extract are bound to phosphatidylcholine
– an emulsifying compound derived from soy. Phytosomes
™ are better absorbed, have greater activity and are
better utilized by the body than either the herbal material
or phosphatidylcholine alone.
Bastyr University: The Bastyr
Hepatitis C Clinic is treating and monitoring patients in
order to “evaluate a science based naturopathic medical
protocol for the treatment of people diagnosed with hepatitis
C”. The protocol calls for 360mg of Siliphos ®–
the exact dosage found in SuperSiliphos.
Clinical Studies: Pharmacological
and toxicological results, added to those found from pharmacokinetic
studies, have provided the basis for clinical testing of SILIPHOS
®. Clinical studies have been performed
to evaluate the properties of this new complex in subjects
with “pathological” impairment of liver function.
The results, including the optimal tolerability obtained in
these “extreme” clinical situations, give strong
support for the use of SILIPHOS ®
for all liver concerns.
What is the form of silymarin that
you recommend?
Recently, a new form of silymarin has emerged that may provide
the greatest benefit. The new form binds silybin, the key
component of silymarin, to phosphatidylcholine, the key component
of our cellular membranes throughout the body. The result
is a product known as SILIPHOS ®.
Current research indicates that SILIPHOS ®
is better absorbed and produces better results than other
silymarin or milk thistle extracts.
What is the evidence to support the
claim that SILIPHOS ® is better?
Several human and animal studies have shown SILIPHOS ®
is better absorbed. In one study, the excretion of silybin
in the bile was evaluated in patients undergoing gallbladder
removal because of gallstones. A special drainage tube, the
T-tube, was used to get the samples of bile necessary. Patients
were given either a single dose of the SILIPHOS ®
or silymarin. The amount of silybin recovered in the bile
within 48 hours was 11% for the SILIPHOS ®
group and 3% for the silymarin group.
In another study designed to assess the absorption
of SILIPHOS ®, plasma silybin levels
were determined after administration of single oral doses
of SILIPHOS ®and a similar amount
of silymarin to 9 healthy volunteers. The authors concluded
SILIPHOS ®was absorbed roughly 7
times greater than regular milk thistle extracts standardized
to contain 70-80% silymarin.
Are there any studies showing better
results with SILIPHOS?
Several clinical studies have also shown SILIPHOS ®
to produce better results than regular silymarin extracts.
In one study of 232 patients with chronic hepatitis (viral,
alcohol, or drug induced) treated with SILIPHOS
® at a dosage either 120mg twice daily or 120mg
three times daily for up to 120 days, liver function returned
to normal faster in the patients taking SILIPHOS ®
compared to a group of controls (49 treated with a commercially
available milk thistle extract standardized to contain 70%
silymarin; 117 untreated or given placebo).
Better results were also seen in a preliminary
study in patients with chronic viral hepatitis (3 with hepatitis
B, 3 with both hepatitis B and hepatitis C, and 2 with hepatitis
C) given SILIPHOS ® for 2 months.
After Treatment, serum malondialdehyde levels (an indicator
of lipid peroxidation) decreased by 36%, and the quantitative
liver function evaluation, as expressed by galactose elimination
capacity, increased by 15%. A statistically significant reduction
of liver enzymes was also seen: AST decreased 17% and ALT
decreased 16%.
In another study designed primarily to evaluate
the dose-response relationship of SILIPHOS ®,
positive effects were again displayed at a level better than
those reported for milk thistle extracts containing 70-80%
silymarin. In the study, patients with chronic hepatitis due
to either a virus or alcohol were given different doses of
SILIPHOS ®: 20 patients received
80mg twice daily, 20 patients received 120 mg twice daily,
and 20 patients received 120mg three times daily for two weeks.
At all tested doses, SILIPHOS ®
produced a remarkable and statistically significant decrease
of mean serum and total bilirubin levels. When used at the
dose of 240 or 360mg per day, it also resulted in a remarkable
and statistically significant decrease of the ALT and GGTP
liver enzymes. These results indicate that even short-term
treatment of viral or alcohol-induced hepatitis with relative
low doses of phosphatidylcholine bound silymarin can be effective,
but for the best results higher doses are indicated.
What is the dosage recommendation
for SuperSiliphos?
For general support for the liver and detoxification, 120mg
of SILIPHOS ® is recommended. When
additional support is needed the dosage recommendation is
360mg three times per day.
How does better absorption related
to better results?
The effectiveness of any herbal product (or medication) is
dependent upon delivering an effective level of the active
compounds. For milk thistle, this means delivering an effective
level of silybin;… It only makes sense that if you can
increase the absorption and utilization of these components
you will see better results.
Background Information 1,
2, 3,
4, 5
The
information found on these materials
has not been evaluated by the Food and Drug Administration.
This product is not intended to diagnose, treat, cure or prevent
any disease
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